What is a Secondary Attack Rate?
I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Liu T Use the link below to share a full-text version of this article with your friends and colleagues. Diagrammatic representation of SAR in household contact is presented as Figure 2. , Wang W This could be possibly due to their active involvement in the care taking activities of the cases that may have resulted into prolonged very close physical contact with the index cases and hence longer exposure to the virus.25,26 It is known that old age and comorbid conditions are independent risk factors of COVID-19 infections and hence it explains higher transmission rate in elderly in household SAR as well.27–30 This resulted in higher fatality rate in elderly as well.8,31–35 It was found that SARs in asymptomatic contacts were significantly lower than the household contacts of the symptomatic cases, where time for symptom onset in index case did not alter the rate of secondary transmission in contacts.23 Li et al.22 showed that the median time from symptom onset in index cases to symptom onset in household contacts was 6 days, though it varied somewhat from study to study. Conclusion: SARS-CoV-2 is more transmissible in households than SARS-CoV and MERS-CoV, and the elderly ≥60 years old are the most vulnerable to household transmission. , et al.
, Cao TZ
The household transmission rate (secondary attack rate) was defined as the percentage of household members who had laboratory-confirmed pandemic (H1N1) 2009 infection 1-7 days after the onset of symptoms in the index patient. , et al. After initial screening of 326 articles, 13 eligible studies were included in the final evidence synthesis. Martins-Filho PR
, Zhang ZB , Li Q Indian Institute of Public Health Gandhinagar. Studies not reporting quantitative statistics regarding SARs, providing SARs in close contacts but not in household contacts, were excluded from evidence synthesis. Diagrammatical presentation of household transmission of COVID-19. This meta-analysis was published as a preprint and thus, had not yet undergone peer review. , et al. email: Search for other works by this author on: Persistent vegetative state after brain damage: a syndrome in search of a name, The scientific literature on Coronaviruses, COVID-19 and its associated safety-related research dimensions: a scientometric analysis and scoping review, A review of modern technologies for tackling COVID-19 pandemic, Active case finding with case management: the key to tackling the COVID-19 pandemic, COVID-19: learning from lessons to guide treatment and prevention interventions, CMMID COVID-19 working group.
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